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Panobinostat

Cat. No.：404950-80-7

  • CAS No. ：404950-80-7

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    • 产品名称: Panobinostat
      CAS No.: 404950-80-7
      Chemical Name:
      Synonyms:帕比司他; LBH589; NVP-LBH589
      分子量:349.43
      分子式:C₂₁H₂₃N₃O₂
      SMILES:O=C(/C=C/C1=CC=C(CNCCC2=C(NC3=C2C=CC=C3)C)C=C1)NO
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Wang, H., Yu, N., Chen, D., et al.Discovery of (2E)-3-{2-butyl-1-[2-diethylamino)ethyl]-1H-benzamidazol-5-yl}-N-hydroxyacrylamide (SB939), an orally active histone deacetylase inhibitor with a superior preclinical profileJ. Med. Chem.54(13),4694-4720(2011)', 'Crisanti, M.C., Wallace, A.F., Kapoor, V., et al.The HDAC inhibitor panobinostat (LBH589) inhibits mesothelioma and lung cancer cells in vitro and in vivo with particular efficacy for small cell lung cancerMol. Cancer Ther.8(8),2221-2231(2009)
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