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Efavirenz

Cat. No.：154598-52-4

  • CAS No. ：154598-52-4

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    • 产品名称: Efavirenz
      CAS No.: 154598-52-4
      Chemical Name:
      Synonyms:依法韦仑; DMP 266; EFV; L-743726
      分子量:315.68
      分子式:C₁₄H₉ClF₃NO₂
      SMILES:ClC1=CC=C(NC(O[C@]2(C#CC3CC3)C(F)(F)F)=O)C2=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Young, S.D., Britcher, S.F., Tran, L.O., et al.L-743,726 (DMP-266): A novel, highly potent nonnucleoside inhibitor of the human immunodeficiency virus type 1 reverse transcriptaseAntimicrob. Agents Chemother.39(12),2602-2605(1995)', 'Grobler, J.A., Dornadula, G., Rice, M.R., et al.HIV-1 reverse transcriptase plus-strand initiation exhibits preferential sensitivity to non-nucleoside reverse transcriptase inhibitors in vitroJ. Biol. Chem.282(11),8005-8010(2007)', 'Goffinet, C., Allespach, I., and Keppler, O.T.HIV-susceptible transgenic rats allow rapid preclinical testing of antiviral compounds targeting virus entry or reverse transcriptionProc. Natl. Acad. Sci. USA104(3),1015-1020(2007)', 'Sheran, M.The nonnucleoside reverse transcriptase inhibitors efavirenz and nevirapine in the treatment of HIVHIV Clin.Trials6(3),158-168(2005)', 'Rakhmanina, N.Y., and van den Anker, J.N.Efavirenz in the therapy of HIV infectionExpert Opin. Drug Metab. Toxicol.6(1),95-103(2010)
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