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Carebastine

Cat. No.：90729-42-3

  • CAS No. ：90729-42-3

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    • 产品名称: Carebastine
      CAS No.: 90729-42-3
      Chemical Name:
      Synonyms:
      分子量:499.64
      分子式:C₃₂H₃₇NO₄
      SMILES:O=C(CCCN1CCC(OC(C2=CC=CC=C2)C3=CC=CC=C3)CC1)C4=CC=C(C=C4)C(C)(C(O)=O)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Vincent, J., Liminana, R., Meredith, P.A., et al.The pharmacokinetics, antihistamine and concentration-effect relationship of ebastine in healthy subjectsBr. J. Clin. Pharmacol.26(5),497-502(1988)', 'Liu, K.-H., Kim, M.-G., Lee, D.-J., et al.Characterization of ebastine, hydroxyebastine, and carebastine metabolism by human liver microsomes and expressed cytochrome P450 enzymes: Major roles for CYP2J2 and CYP3ADrug. Metab. Dispos.34(11),1793-1797(2006)', 'Hishinuma, S., Kosaka, K., Akatsu, C., et al.Asp73-dependent and -independent regulation of the affinity of ligands for human histamine H1 receptors by Na+Biochem. Pharmacol.128,46-54(2017)', 'Yaku, I., Ishii, K., Seto, Y., et al.Pharmacological study of ebastine, a novel histamine H1-receptor antagonistNihon Yakurigaku Zasshi103(3),121-135(1994)', 'Yamauchi, Y., Fujikura, T., and Shimosawa, T.The effect of H1 antagonists carebastine and olopatadine on histamine induced expression of CC chemokines in cultured human nasal epithelial cellsAllergol. Int.56(2),171-177(2007)
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