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Astemizole

Cat. No.：68844-77-9

  • CAS No. ：68844-77-9

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    • 产品名称: Astemizole
      CAS No.: 68844-77-9
      Chemical Name:
      Synonyms:R 43512
      分子量:458.57
      分子式:C₂₈H₃₁FN₄O
      SMILES:COC1=CC=C(CCN2CCC(NC3=NC4=CC=CC=C4N3CC5=CC=C(F)C=C5)CC2)C=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Ahn, H.S., and Barnett, A.Selective displacement of [3H]mepyramine from peripheral vs. central nervous system receptors by loratadine, a non-sedating antihistamineEur. J. Pharmacol.127(1-2),153-155(1986)', 'Kubo, N., Shirakawa, S., Kuno, T., et al.Antimuscarinic effects of antihistamines: Quantitative evaluation by receptor-binding assayJpn. J. Pharmacol.43(3),277-282(1987)', 'Du, L.P., Tsai, K.C., Li, M.Y., et al.The pharmacophore hypotheses of IKr potassium channel blockers: Novel class III antiarrhythmic agentsBioorg. Med. Chem. Lett.14(18),4771-4777(2004)', 'Ficker, E., Obejero-Paz, C.A., Zhao, S., et al.The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutationsJ. Biol. Chem.277(7),4989-4998(2002)', 'García-Quiroz, J., García-Becerra, R., Santos-Martínez, N., et al.In vivo dual targeting of the oncogenic Ether-à-go-go-1 potassium channel by calcitriol and astemizole results in enhanced antineoplastic effects in breast tumorsBMC Cancer14,2-10(2014)
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