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Pemirolast potassium

Cat. No.:YN321526

  • CAS No. :100299-08-9

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    • 产品名称: Pemirolast potassium
      CAS No.: 100299-08-9
      Chemical Name: 9-methyl-3-(2H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one, monopotassium salt
      Synonyms:吡嘧司特钾; TWT-8152; BMY 26517
      分子量:266.30
      分子式:C₁₀H₇KN₆O
      SMILES:O=C1C(C2=N[N-]N=N2)=CN=C3N1C=CC=C3C.[K+]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Pemirolast (TWT-8152) 钾盐是H1组胺受体拮抗剂和肥大细胞稳定剂,可作为抗过敏化合物。
      IC50和靶点:
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    • Yanagihara, Y., Kasai, H., Matsui, S., et al.Immunopharmacological studies on TBX, a new antiallergic drug (3). Inhibitory effects on histamine release from lung fragments and bronchoconstriction in guinea pigsJpn. J. Pharmacol.51(1),83-92(1989)

      Tatsushima, Y., Egashira, N., Kawashiri, T., et al.Involvement of substance P in peripheral neuropathy induced by paclitaxel but not oxaliplatinJ. Pharmacol. Exp. Ther.337(1),226-235(2011)

      Minami, K., Hossen, M.A., and Kamei, C.Increasing effect by simultaneous use of levocabastine and pemirolast on experimental allergic conjunctivitis in ratsBiol. Pharm. Bull.28(3),473-476(2005)

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