Fexofenadine hydrochloride
Cat. No.:YN321579
| 产品名称: | Fexofenadine hydrochloride |
| CAS No.: | 153439-40-8 |
| Chemical Name: | 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-benzeneacetic acid, monohydrochloride |
| Synonyms: | 盐酸非索非那定; MDL-16455 hydrochloride; Terfenadine carboxylate hydrochloride |
| 分子量: | 538.12 |
| 分子式: | C₃₂H₄₀ClNO₄ |
| SMILES: | O=C(O)C(C)(C)C1=CC=C(C(O)CCCN2CCC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)CC2)C=C1.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fexofenadine hydrochloride (MDL-16455 hydrochloride) 是一种H1R拮抗剂,可用于季节性过敏性鼻炎和慢性特发性荨麻疹 (针对年龄大于16岁的人) 的研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Church, M.K., and Church, D.S.Pharmacology of antihistaminesIndian J. Dermatol.58(3),219-224(2013)
Lai, W.S., Lin, Y.Y., Chu, Y.H., et al.Efficacy of fexofenadine in isolated rat tracheasRhinology51(4),376-380(2013)
Koh, S.J., Kim, J.W., Kim, B.G., et al.Fexofenadine regulates nuclear factor-κB signaling and endoplasmic reticulum stress in intestinal epithelial cells and ameliorates acute and chronic colitis in miceJ. Pharmacol. Exp. Ther.352(3),455-461(2015)