Tucatinib
Cat. No.：YN340190
CAS No. ：937263-43-9
规格
价格(RMB)
库存
| 产品名称: | Tucatinib |
| CAS No.: | 937263-43-9 |
| Chemical Name: | N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine |
| Synonyms: | Irbinitinib; ARRY-380; ONT-380 |
| 分子量: | 480.52 |
| 分子式: | C₂₆H₂₄N₈O₂ |
| SMILES: | CC1=CC(NC2=C3C=C(NC4=NC(C)(C)CO4)C=CC3=NC=N2)=CC=C1OC5=CC6=NC=NN6C=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tucatinib (Irbinitinib; ARRY-380; ONT-380) 是有效，选择性的HER2抑制剂，IC50为8 nM。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Pheneger, T., Bouhana, K., Anderson, D., et al.Abstract #1795: In vitro and in vivo activity of ARRY-380: A potent, small molecule inhibitor of ErbB2AACR Cancer Res.69(9),1795(2009)
