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Hesperadin

Cat. No.：422513-13-1

  • CAS No. ：422513-13-1

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    • 产品名称: Hesperadin
      CAS No.: 422513-13-1
      Chemical Name:
      Synonyms:橙皮甙，橙皮苷
      分子量:516.65
      分子式:C₂₉H₃₂N₄O₃S
      SMILES:O=C1NC2=CC=C(C=C2/C1=C(NC3=CC=C(C=C3)CN4CCCCC4)\C5=CC=CC=C5)NS(CC)(=O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Hauf, S., Cole, R.W., LaTerra, S., et al.The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpointJ. Cell. Biol.161(2),281-294(2003)', 'Jetton, N., Rothberg, K.G., Hubbard, J.G., et al.The cell cycle as a therapeutic target against Trypanosoma brucei: Hesperadin inhibits Aurora kinase-1 and blocks mitotic progression in bloodstream formsMol. Microbiol.72(2),442-458(2009)', 'Girdler, F., Gascoigne, K.E., Eyers, P.A., et al.Validating Aurora B as an anti-cancer drug targetJ. Cell Sci.119(Pt 17),3664-3675(2006)', 'Patel, G., Roncal, N.E., Lee, P.J., et al.Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discoveryMedchemcomm.5(5),655-658(2014)', 'Hu, Y., Zhang, J., Musharrafieh, R., et al.Chemical genomics approach leads to the identification of hesperadin, an Aurora B kinase inhibitor, as a broad-spectrum influenza antiviralInt. J. Mol. Sci.18(9),pii: E1929(2017)
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