TRAF-STOP inhibitor 6877002
Cat. No.：YN410015
CAS No. ：433249-94-6
| 产品名称: | TRAF-STOP inhibitor 6877002 |
| CAS No.: | 433249-94-6 |
| Chemical Name: | 6877002; CD40-TRAF6 signaling inhibitor; |
| Synonyms: | CD40-TRAF6 inhibitor |
| 分子量: | 251.32 |
| 分子式: | C₁₇H₁₇NO |
| SMILES: | O=C(C1=CC=CC=C1)/C=C/NC2=C(C=CC(C)=C2)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TRAF-STOP inhibitor 6877002，一种抑制CD40-TRAF6相互作用的选择性抑制剂，从专利 WO2014033122A1 中获得，抑制 RAW 细胞中NF-κB活化，化合物VII。TRAF-STOP 6877002 可阻止小鼠中已发生的动脉粥样硬化恶化，减少白细胞募集并减少巨噬细胞活化；减少动脉粥样硬化斑块中的巨噬细胞增殖。 |
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Zarzycka, B., et al.: J. Chem. Inf. Model., 55, 294 (2015)
