Pyrrolidinedithiocarbamate ammonium
Cat. No.：YN410076
| 产品名称: | Pyrrolidinedithiocarbamate ammonium |
| CAS No.: | 5108-96-3 |
| Chemical Name: | 1-pyrrolidinecarbodithioic acid, monoammonium salt |
| Synonyms: | 吡咯烷二硫代氨基甲酸铵; Ammonium pyrrolidinedithiocarbamate; PDTC ammonium; APDC |
| 分子量: | 164.29 |
| 分子式: | C₅H₁₂N₂S₂ |
| SMILES: | SC(N1CCCC1)=S.N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pyrrolidinedithiocarbamate ammonium (Ammonium pyrrolidinedithiocarbamate) 是选择性的NF-κB抑制剂。 |
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Schreck, R., Meier, B., Männel, D.N., et al.Dithiocarbamates as potent inhibitors of nuclear factor κΒ activation in intact cellsJ. Exp. Med.175(5),1181-1194(1992)
Ziegler-Heitbrock, H.W.L., Sternsdorf, T., Liese, J., et al.Pyrrolidine dithiocarbamate inhibits NF-κΒ mobilization and TNF production in human monocytesJ. Immunol.151(12),6986-6993(1993)
Moon, S.-K., Jung, S.-Y., Choi, Y.-H., et al.PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21Cip1 expression: Involvement of p38 mitogen activated protein kinaseJ. Cell. Physiol.198(2),310-323(2004)
Xu, S., Liu, Z., Huang, Y., et al.Tanshinone II-A inhibits oxidized LDL-induced LOX-1 expression in macrophages by reducing intracellular superoxide radical generation and NF-κB activationTransl. Res.160(2),114-124(2012)
