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Forsythoside B

Cat. No.:YN410090

  • CAS No. :81525-13-5

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    • 参考文献
    • 产品名称: Forsythoside B
      CAS No.: 81525-13-5
      Chemical Name: 2-(3,4-dihydroxyphenyl)ethyl O-D-apio-β-D-furanosyl-(1→6)-O-[6-deoxy-α-L-mannopyranosyl-(1→3)]-β-D-glucopyranoside, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
      Synonyms:连翘酯苷 B
      分子量:756.70
      分子式:C₃₄H₄₄O₁₉
      SMILES:OC1=C(O)C=C(/C=C/C(O[C@H]2[C@H](O[C@]3([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H](O)[C@H](OCCC4=CC=C(O)C(O)=C4)O[C@@H]2CO[C@H]5[C@H](O)[C@](CO)(O)CO5)=O)C=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Forsythoside B 是传统中药植物独一味的叶子中分离的苯乙醇苷。独一味可用于炎症疾病和促进血液循环的研究。Forsythoside B 可抑制TNF-alpha,IL-6,IκB, 调节NF-κB。
      IC50和靶点:
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    • Çaliş, İ., Hosny, M., Khalifa, T., et al.Phenylpropanoid glycosides from Marrubium alyssonPhytochemistry31(10),3624-3626(1992)

      Li, X., Xie, Y., Li, K., et al.Antioxidation and cytoprotection of acteoside and its derivatives: Comparison and mechanistic chemistryMolecules23(2),498(2018)

      Zhang, H., Sun, X., Qi, H., et al.Pharmacological inhibition of the temperature-sensitive and Ca2+-permeable transient receptor potential vanilloid TRPV3 channel by natural forsythoside B attenuates pruritus and cytotoxicity of kratinocytesJ. Pharmacol. Exp. Ther.368(1),21-31(2018)

      Jiang, W.-L., Yong-Xu, Zhang, S.-P., et al.Forsythoside B protects against experimental sepsis by modulating inflammatory factorsPhytother. Res.26(7),981-987(2012)

      Jiang, W.-L., Tian, J.-W., Fu, F.-h., et al.Neuroprotective efficacy and therapeutic window of Forsythoside B: In a rat model of cerebral ischemia and reperfusion injuryEur. J. Pharmacol.640(1-3),75-81(2010)

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