Neferine
Cat. No.：YN410104
CAS No. ：2292-16-2
| 产品名称: | Neferine |
| CAS No.: | 2292-16-2 |
| Chemical Name: | 4-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]oxy]-phenol |
| Synonyms: | 甲基莲心碱; (-) |
| 分子量: | 624.77 |
| 分子式: | C₃₈H₄₄N₂O₆ |
| SMILES: | OC1=CC=C(C[C@@H]2N(C)CCC3=C2C=C(OC)C(OC)=C3)C=C1OC4=CC5=C(C=C4OC)CCN(C)[C@@H]5CC6=CC=C(OC)C=C6 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Neferine 是一种双苄基异喹啉类生物碱。Neferine 强效抑制NF-κB激活。 |
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Yang, R.-P., Zhou, Y.-J., Song, W., et al.Pharmacological actions of neferine in the modulation of human platelet functionEur. J. Pharmacol.862,172626(2019)
Tang, Y.-S., Zhao, Y.-H., Zhong, Y., et al.Neferine inhibits LPS-ATP-induced endothelial cell pyroptosis via regulation of ROS/NLRP3/Caspase-1 signaling pathwayInflamm. Res.68(9),727-738(2019)
Park, M., Han, J., and Lee, H.-J.Anti-adipogenic effect of neferine in 3T3-L1 cells and primary white adipocytesNutrients12(6),1858(2020)
Naim, U.M., Yin, H., and Park, S.-Y.Neferine treatment enhances the TRAIL‑induced apoptosis of human prostate cancer cells via autophagic flux and the JNK pathwayInt. J. Oncol.56(5),1152-1161(2020)
Yin, S., Ran, Q., Yang, J., et al.Nootropic effect of neferine on aluminium chloride-induced Alzheimer's disease in experimental modelsJ. Biochem. Mol. Toxicol.34(2),e22429(2020)
