1-Caffeoylquinic acid
Cat. No.：YN410105
| 产品名称: | 1-Caffeoylquinic acid |
| CAS No.: | 1241-87-8 |
| Chemical Name: | (1α,3R,4α,5R)-1-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4,5-trihydroxy-cyclohexanecarboxylic acid |
| Synonyms: | 金银花,1-咖啡酰奎宁酸 |
| 分子量: | 354.31 |
| 分子式: | C₁₆H₁₈O₉ |
| SMILES: | O[C@@H]1[C@H](O)C[C@@](OC(/C=C/C2=CC(O)=C(O)C=C2)=O)(C(O)=O)C[C@H]1O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 1-Caffeoylquinic acid 1-咖啡酰奎宁酸是一种有效的NF-κB抑制剂，对 p105 的 RH 结构域显示高结合亲和力，Ki值为 0.002 μM，结合能为 1.50 Kcal/mol。1-Caffeoylquinic acid 具有抗氧化应激能力。_x000D_ 1-Caffeoylquinic acid 抑制PD-1/PD-L1相互作用。 |
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Lattanzio, V., Cadinali, A., Venere, D.D., et al.Browning phenomena in stored artichoke (Cynara scolymus L.) heads: Enzymic or chemical reactions?Food Chem.50,(1994)
Khan, M.K.A., Ansari, I.A., Khan, M.S., et al.Dietary phytochemicals as potent chemotherapeutic agents against breast cancer: Inhibition of NF-κB pathway via molecular interactions in rel homology domain of its precursor protein p105Pharmacogn. Mag.9(33),51-57(2013)
Han, Y., Gao, Y., He, T., et al.PD-1/PD-L1 inhibitor screening of caffeoylquinic acid compounds using surface plasmon resonance spectroscopyAnal. Biochem.547,52-56(2018)
