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Myrislignan

Cat. No.:YN410110

  • CAS No. :171485-39-5

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    • 生物活性
    • 参考文献
    • 产品名称: Myrislignan
      CAS No.: 171485-39-5
      Chemical Name: αR-[(1S)-1-[2,6-dimethoxy-4-(2-propen-1-yl)phenoxy]ethyl]-4-hydroxy-3-methoxy-benzenemethanol
      Synonyms:
      分子量:374.43
      分子式:C₂₁H₂₆O₆
      SMILES:C[C@@H]([C@@H](C1=CC(OC)=C(O)C=C1)O)OC(C(OC)=CC(CC=C)=C2)=C2OC
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Myrislignan 是从Myristica fragransHoutt 分离得到的一种木酚素,具有抗炎活性。Myrislignan 通过抑制NF-kB信号通路的激活,减轻LPS诱导的小鼠巨噬细胞炎症反应。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Suwitchayanon, P., Suenaga, K., Iwasaki, A., et al.Myrislignan, a growth inhibitor from the roots of citronella grassNat. Prod. Commun.12(7),1077-1078(2017)

      Jin, H., Zhu, Z.-G., Yu, P.-J., et al.Myrislignan attenuates lipopolysaccharide-induced inflammation reaction in murine macrophage cells through inhibition of NF-κB signalling pathway activationPhytother. Res.26(9),1320-1326(2012)

      Lu, X., Yang, L., Chen, J., et al.The action and mechanism of myrislignan on A549 cells in vitro and in vivoJ. Nat. Med.71(1),76-85(2017)

      Zhang, J., Si, H., Li., B., et al.Myrislignan exhibits activities against Toxoplasma gondii RH strain by triggering mitochondrial dysfunctionFront. Microbiol.10,2152(2019)

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