Berbamine dihydrochloride
Cat. No.：YN410117
CAS No. ：6078-17-7
| 产品名称: | Berbamine dihydrochloride |
| CAS No.: | 6078-17-7 |
| Chemical Name: | 3,4,4aS,5,16aR,17,18,19-octahydro-21,22,26-trimethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-12-ol, dihydrochloride |
| Synonyms: | 小檗胺盐酸盐 |
| 分子量: | 681.65 |
| 分子式: | C₃₇H₄₂Cl₂N₂O₆ |
| SMILES: | COC1=C(OC2=CC([C@]3([H])CC(C=C4)=CC=C4O5)=C(CCN3C)C=C2OC)C([C@@]6([H])CC7=CC=C(O)C5=C7)=C(CCN6C)C=C1OC.Cl.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Berbamine dihydrochloride 是一种NF-κB抑制剂，具有显着的抗骨髓瘤疗效。 |
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Mou, L., Liang, B., Liu, G., et al.Berbamine exerts anticancer effects on human colon cancer cells via induction of autophagy and apoptosis, inhibition of cell migration and MEK/ERK signalling pathwayJ. BUON24(5),1870-1875(2019)
Huang, L., Yuen, T.T.-T., Ye, Z., et al.Berbamine inhibits SARS-CoV-2 infection by compromising TRPMLs-mediated endolysosomal trafficking of ACE2Signal Transduct. Target. Ther.6(1),168(2021)
Liu, X.-Y., Chen, G.-N., Du, G.-M., et al.Berbamine ameliorates ethanol-induced liver injury by inhibition of hepatic inflammation in miceChin. J. Nat. Med.18(3),186-195(2020)
Saranya, S., Baskaran, R., Poornima, P., et al.Berbamine ameliorates isoproterenol-induced myocardial infarction by inhibiting mitochondrial dysfunction and apoptosis in ratsJ. Cell. Biochem.120(3),3101-3113(2019)
