2'-MeCCPA
Cat. No.：YN1730143
CAS No. ：205171-12-6
| 产品名称: | 2'-MeCCPA |
| CAS No.: | 205171-12-6 |
| Chemical Name: | 2-chloro-N-cyclopentyl-2′-C-methyl-adenosine |
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| 分子量: | 383.82988 |
| 分子式: | C16H22ClN5O4 |
| SMILES: | ClC1=NC(NC2CCCC2)=C3C(N([C@@]4([H])[C@](C)(O)[C@H](O)[C@@H](CO)O4)C=N3)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 2'-MeCCPA 是一种有效且具有选择性的A1 腺苷受体 (A1AR)激动剂。2'-MeCCPA 可有效抑制直接通路介质刺胞神经元 (dMSNs) 和间接通路介质刺胞神经元 (iMSNs) 中 cAMP 的调节。 |
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Franchetti, P., Cappellacci, L., Marchetti, S., et al.2'-C-Methyl analogues of selective adenosine receptor agonists: Synthesis and binding studiesJ. Med. Chem.41(10),1708-1715(1998)
Maione, S., de Novellis, V., Cappellacci, L., et al.The antinociceptive effect of 2-chloro-2'-C-methyl-N6-cyclopentyladenosine (2'-Me-CCPA), a highly selective adenosine A1 receptor agonist, in the ratPain131(3),281-292(2007)
