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(+)-(3R,8S)-Falcarindiol

Cat. No.:YN1710051

  • CAS No. :225110-25-8

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    • 参考文献
    • 产品名称: (+)-(3R,8S)-Falcarindiol
      CAS No.: 225110-25-8
      Chemical Name: (3R,8S,9Z)-1,9-heptadecadiene-4,6-diyne-3,8-diol
      Synonyms:(3R,8S
      分子量:260.37126
      分子式:C17H24O2
      SMILES:CCCCCCC/C=C\[C@H](O)C#CC#C[C@H](O)C=C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: (+)-(3R,8S)-Falcarindiol 是从胡萝卜中得到的聚乙炔,具有抗分歧杆菌 (antimycobacterial) 作用,对Mycobacterium tuberculosisH37Ra 的最低抑制浓度 MIC 和 IC50值分别为 24 μM 和 6 μM。具有抗肿瘤和抗炎作用。
      IC50和靶点:
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    • O'Neill, T., Johnson, J.A., Webster, D., et al.The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarinsJ. Ethnopharmacol.147(1),232-237(2013)

      Zheng, X., Zheng, X., Zhang, C., et al.Cytotoxic polyacetylenes isolated from the roots and rhizomes of Notopterygium incisumChinese Chem. Lett.30(2),428-430(2019)

      Tamura, S., Ohno, T., Hattori, Y., et al.Establishment of absolute stereostructure of falcarindiol, algicidal principle against Heterocapsa circularisquama from Notopterygii RhizomaTetrahedron Lett.51(11),1523-1525(2010)

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