PF-562271
Cat. No.：YN440096
CAS No. ：717907-75-0
| 产品名称: | PF-562271 |
| CAS No.: | 717907-75-0 |
| Chemical Name: | N-[3-[[[2-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-methanesulfonamide; N-Methyl-N-[3-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]pyridin-2 |
| Synonyms: | PF562271,PF 562271 |
| 分子量: | 507.49 |
| 分子式: | C₂₁H₂₀F₃N₇O₃S |
| SMILES: | CS(=O)(N(C)C1=NC=CC=C1CNC2=NC(NC3=CC4=C(C=C3)NC(C4)=O)=NC=C2C(F)(F)F)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-562271 是一种有效，可逆，ATP 竞争性的FAK和Pyk2激酶抑制剂，IC50分别为 1.5 nM 和 13 nM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Infante, J., et al.: J. Clin. Oncol., 30, 1527 (2012)
Lee, B., et al.: Mol. Cancer Ther., 13, 190 (2014)
