Amiselimod hydrochloride
Cat. No.：YN321087
CAS No. ：942398-84-7
规格
价格(RMB)
库存
| 产品名称: | Amiselimod hydrochloride |
| CAS No.: | 942398-84-7 |
| Chemical Name: | 2-amino-2-[2-[4-(heptyloxy)-3-(trifluoromethyl)phenyl]ethyl]-1,3-propanediol, monohydrochloride |
| Synonyms: | MT-1303 hydrochloride |
| 分子量: | 413.90 |
| 分子式: | C₁₉H₃₁ClF₃NO₃ |
| SMILES: | OCC(CCC1=CC=C(OCCCCCCC)C(C(F)(F)F)=C1)(N)CO.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Amiselimod hydrochloride 是一个新颖的S1P1受体的调节器。 |
| IC50和靶点: | |
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Sugahara, K., Maeda, Y., Shimano, K., et al.Amiselimod, a novel sphingosine 1-phosphate receptor-1 modulator, has potent therapeutic efficacy for autoimmune diseases, with low bradycardia riskBr. J. Pharmacol.174(1),15-27(2017)
Shimano, K., Maeda, Y., Kataoka, H., et al.Amiselimod (MT-1303), a novel sphingosine 1-phosphate receptor-1 functional antagonist, inhibits progress of chronic colitis induced by transfer of CD4+CD45RBhigh T cellsPLoS One14(12),e0226154(2019)
