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Chelerythrine chloride

Cat. No.：3895-92-9

  • CAS No. ：3895-92-9

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    • 产品名称: Chelerythrine chloride
      CAS No.: 3895-92-9
      Chemical Name:
      Synonyms:盐酸白屈菜红碱
      分子量:383.82
      分子式:C₂₁H₁₈ClNO₄
      SMILES:C[N+]1=CC2=C(C(OC)=CC=C2C3=C1C4=CC5=C(OCO5)C=C4C=C3)OC.[Cl-]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Herbert, J.M., Augereau, J.M., Gleye, J., et al.Chelerythrine is a potent and specific inhibitor of protein kinase CBiochem. Biophys. Res. Commun.172,993-999(1990)', 'Chan, S.L., Lee, M.C., Tan, K.O., et al.Identification of chelerythrine as an inhibitor of BclXL functionJ. Biol. Chem.278(23),20453-20456(2003)', 'Lee, S.K., Qing, W.G., Mar, W., et al.Angoline and chelerythrine, benzophenanthridine alkaloids that do not inhibit protein kinase CJ. Biol. Chem.273(31),19829-19833(1998)', 'Chmura, S.J., Dolan, M.E., Cha, A., et al.In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivoClin. Cancer Res.6,737-742(2012)', 'Yu, R., Mandlekar, S., Tan, T.H., et al.Activation of p38 and c-Jun N-terminal kinase pathways and induction of apoptosis by chelerythrine do not require inhibition of protein kinase CJ. Biol. Chem.275(13),9612-9619(2000)', 'Zhang, Z.F., Guo, Y., Zhang, J.b., et al.Induction of apoptosis by chelerythrine chloride through mitochondrial pathway and Bcl-2 family proteins in human hepatoma SMMC-7721 cellArch. Pharm. Res.34(5),791-800(2011)
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