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Bisindolylmaleimide I

Cat. No.:133052-90-1

  • CAS No. :133052-90-1

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    • 产品名称: Bisindolylmaleimide I
      CAS No.: 133052-90-1
      Chemical Name:
      Synonyms:GF109203X; Go 6850
      分子量:412.48
      分子式:C₂₅H₂₄N₄O₂
      SMILES:O=C(C(C1=CN(CCCN(C)C)C2=C1C=CC=C2)=C3C4=CNC5=C4C=CC=C5)NC3=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Toullec, D., Pianetti, P., Coste, H., et al.The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase CJ. Biol. Chem.266(24),15771-15781(1991)', 'Hers, I., Tavaré, J.M., and Denton, R.M.The protein kinase C inhibitors bisindolylmaleimide I (GF 109203x) and IX (Ro 31-8220) are potent inhibitors of glycogen synthase kinase-3 activityFEBS Lett.460(3),433-436(1999)', 'Coultrap, S.J., Sun, H., Tenner, T.E., et al.Competitive antagonism of the mouse 5-hydroxytryptamine receptor by bisindolylmaleimide I, a "selective" protein kinase C inhibitorJ. Pharmacol. Exp. Ther.290(1),76-82(1999)
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