PF-5274857
Cat. No.：YN450079
CAS No. ：1373615-35-0
规格
价格(RMB)
库存
| 产品名称: | PF-5274857 |
| CAS No.: | 1373615-35-0 |
| Chemical Name: | |
| Synonyms: | PF-5274857 freebase |
| 分子量: | 436.96 |
| 分子式: | C₂₀H₂₅ClN₄O₃S |
| SMILES: | O=C(N1CCN(C2=NC=C(Cl)C(C3=NC=C(C)C=C3C)=C2)CC1)CCS(=O)(C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-5274857 是一种有效的、选择性的、具有口服活性和可透过血脑屏障的Smo拮抗剂，IC50值为 5.8 nM，Ki值为 4.6 nM。PF-5274857 有潜力用于包括激活的 Hh 途径驱动的脑肿瘤和脑转移在内的多种肿瘤的研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
