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CX-5461

Cat. No.：1138549-36-6

  • CAS No. ：1138549-36-6

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    • 产品名称: CX-5461
      CAS No.: 1138549-36-6
      Chemical Name:
      Synonyms:CX5461;CX-5461;2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxamide;2-(4-methyl-1,4-diazepan-1-yl)-N-[(5-methylpyrazin-2-yl)methyl]-5-oxo-[1,3]benzothiazolo[3,2-a][1,8]naphthyri
      分子量:513.61
      分子式:C₂₇H₂₇N₇O₂S
      SMILES:CC1=NC=C(CNC(C2=C3N(C4=NC(N5CCN(CCC5)C)=CC=C4C2=O)C6=C(S3)C=CC=C6)=O)N=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Drygin, D., Lin, A., Bliesath, J., et al.Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growthCancer Res.71(4),1418-1430(2011)', 'Haddach, M., Schwaebe, M.K., Michaux, J., et al.Discovery of CX-5461, the first direct and selective inhibitor of RNA polymerase I, for cancer therapeuticsACS Med. Chem. Lett.3(7),602-606(2012)
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