Lersivirine
Cat. No.：YN250583
CAS No. ：473921-12-9
规格
价格(RMB)
库存
| 产品名称: | Lersivirine |
| CAS No.: | 473921-12-9 |
| Chemical Name: | 5-[[3,5-diethyl-1-(2-hydroxyethyl)-1H-pyrazol-4-yl]oxy]-1,3-benzenedicarbonitrile |
| Synonyms: | UK-453061 |
| 分子量: | 310.35 |
| 分子式: | C₁₇H₁₈N₄O₂ |
| SMILES: | CCC1=NN(CCO)C(CC)=C1OC2=CC(C#N)=CC(C#N)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lersivirine (UK-453061) 是非核苷逆转录的抑制剂 (NNRTI;IC50=119 nM)，对 NNRTI 耐药病毒具有优异的抑制效果。Lersivirine 对野生型人类免疫缺陷病毒 (HIV) 和临床相关 NNRTI 耐药菌株显示出强大的抗逆转录病毒活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Corbau, R., Mori, J., Phillips, C., et al.Lersivirine, a nonnucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus type 1Antimicrob. Agents Chemother.54(10),4451-4463(2010)
