Hexestrol
Cat. No.：YN482055
| 产品名称: | Hexestrol |
| CAS No.: | 84-16-2 |
| Chemical Name: | rel-4,4′-[(1R,2S)-1,2-diethyl-1,2-ethanediyl]bis-phenol |
| Synonyms: | Bibenzyl |
| 分子量: | 270.37 |
| 分子式: | C₁₈H₂₂O₂ |
| SMILES: | CC[C@H](C1=CC=C(O)C=C1)[C@H](C2=CC=C(O)C=C2)CC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Hexestrol 是一种非甾体合成雌激素，对雌激素受体ERα和ERβ的Ki值均为 0.06 nM。Hexestrol 可用于研究雌激素缺乏引起的疾病，还可增加牛的体重。 |
| IC50和靶点: | [{name:"ERα:0.06 nM (Ki)"},{name: "ERβ:0.06 nM (Ki)"}] |
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| Solvent & Solubility: |
Kuiper, G.G.J.M., Carlsson, B., Grandien, K., et al.Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and βEndocrinology138(3),863-870(1997)
Wiseman, H., and Halliwell, B.Carcinogenic antioxidants. Diethylstilboestrol, hexoestrol and 17 α-ethynyloestradiolFEBES Lett.332(1-2),159-163(1993)
Sato, Y., Murai, T., Oda, T., et al.Inhibition of microtubule polymerization by synthetic estrogens: Formation of a ribbon structureJ. Biochem.101(5),1247-1252(1987)
Liehr, J.G., Ballatore, A.M., Dague, B.B., et al.Carcinogenicity and metabolic activation of hexestrolChem. Biol. Interact.55(1-2),157-176(1985)
