Bavachin
Cat. No.：YN482392
CAS No. ：19879-32-4
| 产品名称: | Bavachin |
| CAS No.: | 19879-32-4 |
| Chemical Name: | (2S)-2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one |
| Synonyms: | 补骨脂二氢黄酮; Corylifolin |
| 分子量: | 324.37 |
| 分子式: | C₂₀H₂₀O₄ |
| SMILES: | O=C1C[C@@H](C2=CC=C(O)C=C2)OC3=CC(O)=C(C/C=C(C)\C)C=C13 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Bavachin 是从补骨脂种子中分离到的黄酮类物质，作为植物雌激素激活雌性激素受体ERα和ERβ，EC50值分别为 320 和 680 nM。 |
| IC50和靶点: | |
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Xin, D., Wang, H., Yang, J., et al.Phytoestrogens from Psoralea corylifolia reveal estrogen receptor-subtype selectivityPhytomedicine17(2),126-131(2010)
Park, J., Kim, D.H., Ahn, H.-N., et al.Activation of estrogen receptor by bavachin from Psoralea corylifoliaBiomol. Ther. (Seoul)20(2),183-188(2012)
Li, W.D., Yan, C.P., Wu, Y., et al.Osteoblasts proliferation and differentiation stimulating activities of the main components of Fructus Psoraleae corylifoliaePhytomedicine21(4),400-405(2014)
Weng, Z.B., Gao, Q.Q., Wang, F., et al.Positive skeletal effect of two ingredients of Psoralea corylifolia L. on estrogen deficiency-induced osteoporosis and the possible mechanisms of actionMol. Cell. Endocrinol.417,103-113(2015)
Choi, J.H., Rho, M.C., Lee, S.W., et al.Bavachin and isobavachalcone, acyl-coenzyme A: Cholesterol acyltransferase inhibitors from Psoralea corylifoliaArch. Pharm. Res.31(11),1419-1423(2008)
