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Genistin

Cat. No.:YN482498

  • CAS No. :529-59-9

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Genistin
      CAS No.: 529-59-9
      Chemical Name: 7-(β-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
      Synonyms:染料木苷;
      分子量:432.38
      分子式:C₂₁H₂₀O₁₀
      SMILES:O=C(C(C1=CC=C(O)C=C1)=COC2=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)=C4)C2=C4O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Genistin (Genistine) 是一种植物雌激素家族的异黄酮,是一种有效的抗脂肪和抗脂肪生成剂。Genistin通过调节ERalpha信号通路抑制乳腺癌细胞生长和促进凋亡细胞死亡。
      IC50和靶点:
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      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Allred, C.D., Ju, Y.H., Allred, K.F., et al.Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genisteinCarcinogenesis22(10),1667-1673(2001)

      Uesugi, T., Toda, T., Tsuji, K., et al.Comparative study on reduction of bone loss and lipid metabolism abnormality in ovariectomized rats by soy isoflavones, daidzin, genistin, and glycitinBiol. Pharm. Bull.24(4),368-372(2001)

      Li, X.h., Zhang, J.C., Sui, S.f., et al.Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblastsActa Pharmacol. Sin.26(9),1081-1086(2005)

      Wong, R.W., and Rabie, A.B.Effect of genistin on bone formationFront. Biosci. (Elite Ed.)2(2),764-770(2010)

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