Coumestrol
Cat. No.：YN482893
CAS No. ：479-13-0
| 产品名称: | Coumestrol |
| CAS No.: | 479-13-0 |
| Chemical Name: | 3,9-dihydroxy-6H-benzofuro[3,2-c][1]benzopyran-6-one |
| Synonyms: | 拟雌内酯 |
| 分子量: | 268.22 |
| 分子式: | C₁₅H₈O₅ |
| SMILES: | O=C1C2=C(OC3=CC(O)=CC=C32)C4=CC=C(O)C=C4O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Coumestrol是大豆产品中存在的植物雌激素。可用于癌症，神经障碍和自身免疫疾病的研究。抑制ES2细胞增殖的IC50值为50 μM。 |
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Chen, H.Y., Dykstra, K.D., Birzin, E.T., et al.Estrogen receptor ligands. Part 1: The discovery of flavanoids with subtype selectivityBioorg. Med. Chem. Lett.14(6),1417-1421(2004)
Hopert, A.C., Beyer, A., Frank, K., et al.Characterization of estrogenicity of phytoestrogens in an endometrial-derived experimental modelEnviron. Health Perspect.106(9),581-586(1998)
Wang, H., Li, H., Moore, L.B., et al.The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptorMol. Endocrinol.22(4),838-857(2008)
