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Zearalanone

Cat. No.:YN483345

  • CAS No. :5975-78-0

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Zearalanone
      CAS No.: 5975-78-0
      Chemical Name: (3S)-3,4,5,6,9,10,11,12-octahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione
      Synonyms:玉米赤霉酮
      分子量:320.38
      分子式:C₁₈H₂₄O₅
      SMILES:O=C(O[C@@H](C)CCC1)C2=C(O)C=C(O)C=C2CCCCCC1=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Zearalenone 是由镰刀菌属Fusarium产生的,在几种谷物中生长的非甾体雌激素霉菌毒素。 Zearalenone 具有较低的急性毒性和致癌性。Zearalenone 对雌激素受体有激动作用,在几种动物中表现出明显的雌激素和合成代谢特性,对动物的生殖系统会产生严重影响。
      IC50和靶点:
      In Vitro:
      In Vivo:
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      Solvent & Solubility:
    • Baldwin, R.S., Williams, R.D., and Terry, M.K.Zeranol: A review of the metabolism, toxicology, and analytical methods for detection of tissue residuesRegul. Toxicol. Pharmacol.3(1),9-25(1983)

      Migdalof, B.H., Dugger, H.A., Heider, J.G., et al.Biotransformation of zeranol: Disposition and metabolism in the female rat, rabbit, dog, monkey and manXenobiotica13(4),209-221(1983)

      Le Guevel, R., and Pakdel, F.Assessment of oestrogenic potency of chemicals used as growth promoter by in-vitro methodsHum. Reprod.16(5),1030-1036(2001)

      Molina-Molina, J.M., Real, M., Jimenez-Diaz, I., et al.Assessment of estrogenic and anti-androgenic activities of the mycotoxin zearalenone and its metabolites using in vitro receptor-specific bioassaysFood Chem. Toxicol.74,233-239(2016)

      Aoyama, K., Ishikuro, E., Noriduki, H., et al.Formation ratios of zearalanone, zearalenols, and zearalanols versus zearalenone during incubation of Fusarium semitectum on sorghum and ratios in naturally contaminated sorghumFood Hyg. Saf. Sci.56(6),247-251(2015)

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