(Rac)-Acolbifene
Cat. No.:YN481525
| 产品名称: | (Rac)-Acolbifene | 
| CAS No.: | 151533-34-5 | 
| Chemical Name: | 3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol; EM 343 | 
| Synonyms: | EM-343; (Rac)-EM-652 | 
| 分子量: | 457.56 | 
| 分子式: | C₂₉H₃₁NO₄ | 
| SMILES: | OC1=CC=C2C(C)=C(C3=CC=C(O)C=C3)C(C4=CC=C(OCCN5CCCCC5)C=C4)OC2=C1 | 
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. | 
| 运输: | Room temperature in continental US; may vary elsewhere. | 
| 产品描述: | (Rac)-Acolbifene (EM-343; (Rac)-EM-652) 是 EM652 (estrogen receptor拮抗剂) 的外消旋形式,具有抗雌激素和雌激素活性。 (Rac)-Acolbifene (EM-343; (Rac)-EM-652) 含哌啶环,具有良好的药理作用,RBA=380。 | 
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | 
Gauthier, S., et al.: J. Enzyme Inhibition Med. Chem., 20, 165 (2005)
Tremblay, G., et al.: Cancer Res., 58, 877 (1998)