Desfesoterodine
Cat. No.：YN321307
CAS No. ：207679-81-0
| 产品名称: | Desfesoterodine |
| CAS No.: | 207679-81-0 |
| Chemical Name: | 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol; (+)-N,N-Diisopropyl-3-(2-hydroxy-5-hydroxymethylphenyl)-3-phenylpropylamine; PNU 200577; |
| Synonyms: | (R)-5-羟甲基托特罗定; PNU-200577; 5-Hydroxymethyl Tolterodine |
| 分子量: | 341.49 |
| 分子式: | C₂₂H₃₁NO₂ |
| SMILES: | OC1=C(C=C(CO)C=C1)[C@@H](C2=CC=CC=C2)CCN(C(C)C)C(C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Desfesoterodine (PNU-200577) 是一种有效的，选择性毒蕈碱受体 (mAChR) 拮抗剂，KB和pA2分别为 0.84 nM 和 9.14。Desfesoterodine 是 Tolterodine (PNU-200583; HY-A0024) 和 Fesoterodine (HY-70053) 的主要药理活性代谢产物。Desfesoterodine 改善大鼠脑梗死诱导膀胱过度活动。 |
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Palmer, L., et al.: J. Pharm. Biomed. Anal., 16, 155 (1997), Hills, C., et al.: Drugs, 55, 813 (1998), Wefer, J., et al.: World J. Urol., 19, 312 (2001),
