Otilonium bromide
Cat. No.：YN321519
CAS No. ：26095-59-0
| 产品名称: | Otilonium bromide |
| CAS No.: | 26095-59-0 |
| Chemical Name: | N,N-diethyl-N-methyl-2-[[4-[[2-(octyloxy)benzoyl]amino]benzoyl]oxy]-ethanaminium, monobromide |
| Synonyms: | 奥替溴铵; Octylonium bromide; SP63 |
| 分子量: | 563.57 |
| 分子式: | C₂₉H₄₃BrN₂O₄ |
| SMILES: | O=C(OCC[N+](CC)(CC)C)C1=CC=C(NC(C2=CC=CC=C2OCCCCCCCC)=O)C=C1.[Br-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Otilonium 溴化物 (SP63) 有抗毒蕈碱活性，可用于解痉。 |
| IC50和靶点: | |
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Martin, M.T., Hove-Madsen, L., and Jimenez, M.Otilonium bromide inhibits muscle contractions via L-type calcium channels in the rat colonNeurogastroenterol. Motil.16(2),175-183(2004)
Strege, P.R., Sha, L., Beyder, A., et al.T-type Ca2+ Channel Modulation by Otilonium BromideAm. J. Physiol. Gastrointest. Liver Physiol.298(5),G706-G713(2010)
Evangelista, S., Giachetti, A., Chapelain, B., et al.Receptor binding profile of otilonium bromidePharmacol. Res.38(2),111-117(1998)
Santicioli, P., Zagorodnyuk, V., Renzetti, A.R., et al.Antimuscarinic, calcium channel blocker and tachykinin NK2 receptor antagonist actions of otilonium bromide in the circular muscle of guinea-pig colonNaunyn-Schmiedebergs Arch. Pharmacol.359(5),420-427(1999)
Pinelli, A., Trivulzio, S., and Vignati, S.Effects exerted by otilonium bromide administration on precipitated opioid withdrawal syndrome in ratsToxicology122(1-2),23-37(1997)
