SB-224289 hydrochloride
Cat. No.：YN320102
CAS No. ：180084-26-8
| 产品名称: | SB-224289 hydrochloride |
| CAS No.: | 180084-26-8 |
| Chemical Name: | [2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl](2,5,6,7-tetrahydro-1'-methylspiro[3H-furo[2,3-f]indole-3,4'-piperidin]-5-yl)-methanone, monohydrochloride |
| Synonyms: | SB-224289A |
| 分子量: | 557.08 |
| 分子式: | C₃₂H₃₃ClN₄O₃ |
| SMILES: | O=C(C1=CC=C(C2=CC=C(C3=NOC(C)=N3)C=C2C)C=C1)N4CCC5=C4C=C6C(OCC67CCN(C)CC7)=C5.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SB-224289 hydrochloride 是一种选择性的5-HT1B receptor拮抗剂，具有抗焦虑作用。 |
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Selkirk, J.V., Scott, C., Ho, M., et al.SB-224289 -- A novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activityBr. J. Pharmacol.125(1),202-208(1998)
Pentkowski, N.S., Harder, B.G., Brunwasser, S.J., et al.Pharmacological evidence for an abstinence-induced switch in 5-HT1B receptor modulation of cocaine self-administration and cocaine-seeking behaviorACS Chem. Neurosci.5(3),168-176(2014)
