Prucalopride succinate
Cat. No.：YN320628
CAS No. ：179474-85-2
| 产品名称: | Prucalopride succinate |
| CAS No.: | 179474-85-2 |
| Chemical Name: | 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide Butanedioic Acid; R 108512; Resolor; |
| Synonyms: | 琥珀酸普芦卡必利; R-108512 |
| 分子量: | 485.96 |
| 分子式: | C₂₂H₃₂ClN₃O₇ |
| SMILES: | O=C(O)CCC(O)=O.O=C(C1=C(OCC2)C2=C(N)C(Cl)=C1)NC3CCN(CCCOC)CC3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Prucalopride琥珀酸盐是5-HT4受体选择高亲和性激动剂，对5-HT4a和5-HT4b的pKi值分别为8.6和8.1。 |
| IC50和靶点: | [{name:"5-HT4A Receptor:8.6 (pKi)"},{name: "5-HT4B Receptor:8.1 (pKi)"}] |
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| Solvent & Solubility: |
Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),
