GSK163090
Cat. No.：YN320857
CAS No. ：844903-58-8
| 产品名称: | GSK163090 |
| CAS No.: | 844903-58-8 |
| Chemical Name: | |
| Synonyms: | GSK163090,GSK-163090,GSK 163090 |
| 分子量: | 415.53 |
| 分子式: | C₂₅H₂₉N₅O |
| SMILES: | O=C1NCCN1C2=CC=CC(CCN3CCN(C4=C5C=CC(C)=NC5=CC=C4)CC3)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK163090 是一种有效的，选择性的和具有口服活性的5-HT1A/1B/1D受体拮抗剂，pKi值分别为 9.4/8.5/9.7。GSK163090 抑制血清素再摄取转运蛋白 (SerT) 的功能活性，其pKi值为 6.1。GSK163090 具有抗抑郁和抗焦虑活性。 |
| IC50和靶点: | [{name:"5-HT1A Receptor:9.4 (pKi)"},{name: "5-HT1B Receptor:8.5 (pKi)"},{name: "5-HT1D Receptor:9.7 (pKi)"},{name: "D2 Receptor:6.3 (pKi)"},{name: "D3 Receptor:6.7 (pKi)"},{name: "5-HT2A Receptor:6 (pKi)"},{name: "5-HT2B Receptor:6.3 (pKi)"},{name: "5-HT2C Receptor:5.8 (pKi)"},{name: "Human 5-HT6 Receptor:<5.3 (pKi)"},{name: "Human 5-HT7 Receptor:6.8 (pKi)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
