Ziprasidone hydrochloride
Cat. No.：YN320880
| 产品名称: | Ziprasidone hydrochloride |
| CAS No.: | 122883-93-6 |
| Chemical Name: | 5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)-ethyl)-6-chloroindolin-2-one Hydrochloride; Azona; CP 88059-1; Zeldox; Zipsydon |
| Synonyms: | 盐酸齐拉西酮; CP-88059 hydrochloride |
| 分子量: | 449.40 |
| 分子式: | C₂₁H₂₂Cl₂N₄OS |
| SMILES: | ClC1=CC2=C(CC(N2)=O)C=C1CCN(CC3)CCN3C4=NSC5=C4C=CC=C5.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ziprasidone (CP 88059) hydrochloride是一种抗精神病药物，是5-HT (serotonin)和多巴胺受体(dopamine receptor) 拮抗剂。Ziprasidone hydrochloride 对大鼠 (Ki: 3.4 nM) 和人 (2.5 nM) 5-HT1A，5-HT2A (0.42 nM) 和 dopamine D2 (4.8 nM) 受体有很高的亲和力。Ziprasidone hydrochloride 是一种去甲肾上腺素再摄取 (norepineph |
| IC50和靶点: | [{name:"Rat 5-HT2A:0.42 nM (Ki)"},{name: "Rat 5-HT1A Receptor:3.4 nM (Ki)"},{name: "Rat D2 Receptor:4.8 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Lee, S.E., et.al: Psychiatry Res., 299, 113830, (2021)
