(Rac)-Rotigotine hydrochloride
Cat. No.：YN320973
CAS No. ：102120-99-0
| 产品名称: | (Rac)-Rotigotine hydrochloride |
| CAS No.: | 102120-99-0 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 351.93 |
| 分子式: | C₁₉H₂₆ClNOS |
| SMILES: | OC1=C2CCC(N(CCC)CCC3=CC=CS3)CC2=CC=C1.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (Rac)-Rotigotine hydrochloride 是 Rotigotine 的外消旋体。Rotigotine 是dopamine receptor激动剂，是5-HT1A receptor的部分激动剂，以及α2B-adrenergic receptor的拮抗剂，Ki值分别为 0.71 nM (dopamine D3 receptor)，4-15 nM (D2，D5，D4 receptors)，83 nM (dopamine D1 receptor)。 |
| IC50和靶点: | [{name:"D3 Receptor:0.71 nM (Ki)"},{name: "D2 Receptor:13.5 nM (Ki)"},{name: "D4 Receptor:3.9-15 nM (Ki)"},{name: "D5 Receptor:5.4 nM (Ki)"},{name: "D1 Receptor:83 nM (Ki)"},{name: "5-HT1A Receptor:30 nM (Ki)"},{name: "5-HT2B Receptor:27 nM (Ki)'}, 'Alpha-2B adrenergic receptor'] |
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