CP-809101 hydrochloride
Cat. No.：YN321004
CAS No. ：1215721-40-6
| 产品名称: | CP-809101 hydrochloride |
| CAS No.: | 1215721-40-6 |
| Chemical Name: | 2-[(3-chlorophenyl)methoxy]-6-(1-piperazinyl)-pyrazine, monohydrochloride |
| Synonyms: | CP809101 hydrochloride;CP 809101 hydrochloride |
| 分子量: | 341.24 |
| 分子式: | C₁₅H₁₈Cl₂N₄O |
| SMILES: | [H]Cl.ClC1=CC(COC2=NC(N3CCNCC3)=CN=C2)=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CP-809101 hydrochloride 是5-HT2受体激动剂，对人5-HT2C/5-HT2B/5-HT2A受体的pEC50分别为9.96/7.19/6.81。 |
| IC50和靶点: | [{name:"5-HT2C Receptor:9.96 (pEC50)"},{name: "5-HT2B Receptor:7.19 (pEC50)"},{name: "5-HT2A Receptor:6.81 (pEC50)"}] |
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Siuciak, J.A., Chapin, D.S., McCarthy, S.A., et al.CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of antipsychotic activityNeuropharmacology52(2),279-290(2007)
Pockros-Burgess, L.A., Pentkowski, N.S., Der-Ghazarian, T., et al.Effects of the 5-HT2C receptor agonist CP809101 in the amygdala on reinstatement of cocaine-seeking behavior and anxiety-like behaviorInt. J. Neuropsychopharmacol.17(11),1751-1762(2014)
Higgins, G.A., Silenieks, L.B., Altherr, E.B., et al.Lorcaserin and CP-809101 reduce motor impulsivity and reinstatement of food seeking behavior in male rats: Implications for understanding the anti-obesity property of 5-HT2C receptor agonistsPsychopharmacology (Berl)233(14),2841-2856(2016)
