Asenapine hydrochloride
Cat. No.：YN321067
CAS No. ：1412458-61-7
规格
价格(RMB)
库存
| 产品名称: | Asenapine hydrochloride |
| CAS No.: | 1412458-61-7 |
| Chemical Name: | |
| Synonyms: | 阿塞那平盐酸盐 |
| 分子量: | 322.23 |
| 分子式: | C₁₇H₁₇Cl₂NO |
| SMILES: | [H]Cl.ClC1=CC2=C(C=C1)OC3=C(C=CC=C3)[C@](C4)([H])[C@]2([H])CN4C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Asenapine hydrochloride，一种抗精神病药物，同时是5-HT(1A, 1B, 2A, 2B, 2C, 5A, 6, 7) 和Dopamine (D2，D3，D4)受体的拮抗剂，对5-HT 受体的Ki值分别为 0.03-4.0 nM，多巴胺受体的Ki值分别为1.3，0.42，1.1 nM。 |
| IC50和靶点: | [{name:"sPLA2:2.5 nM (Ki)"},{name: "5-HT2A Receptor:0.06 nM (Ki)"},{name: "5-HT2C Receptor:0.03 nM (Ki)"},{name: "5-HT7 Receptor:0.13 nM (Ki)"},{name: "D2 Receptor:1.3 nM (Ki)"},{name: "D3 Receptor:0.42 nM (Ki)"},{name: "D4 Receptor:1.1 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
