RU 24969 hemisuccinate
Cat. No.：YN321081
CAS No. ：66611-27-6
| 产品名称: | RU 24969 hemisuccinate |
| CAS No.: | 66611-27-6 |
| Chemical Name: | 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole, butanedioic acid (2:1) |
| Synonyms: | 5-甲氧基-3-(1,2,5,6-四氢-4-吡啶基)-1H-吲哚半琥珀酸盐 |
| 分子量: | 287.34 |
| 分子式: | C₁₄H₁₆N₂O.₁/₂C₄H₆O₄ |
| SMILES: | O=C(O)CCC(O)=O.COC1=CC=C2C(C(C3=CCNCC3)=CN2)=C1.[1/2] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | RU 24969 hemisuccinate 是一种优先的5-HT1B激动剂，Ki值为 0.38 nM，对5-HT1A受体也显示出明显的亲和力 (Ki=2.5 nM)，对脑中其他受体部位的亲和力很低。RU 24969 hemisuccinate 可减少液体消耗并增加向前运动。 |
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Middlemiss, D.N.The putative 5-HT1 receptor agonist, RU 24969, inhibits the efflux of 5-hydroxytryptamine from rat frontal cortex slices by stimulation of the 5-HT autoreceptorJ. Pharm. Pharmacol.37(6),434-437(1985)
Parsons, L.H., Koob, G.F., and Weiss, F.RU 24969, a 5-HT1B/1A receptor agonist, potentiates cocaine-induced increases in nucleus accumbens dopamineSynapse32(2),132-135(1999)
