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Loxapine succinate

Cat. No.:YN321128

  • CAS No. :27833-64-3

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    • 参考文献
    • 产品名称: Loxapine succinate
      CAS No.: 27833-64-3
      Chemical Name: 2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine succinate
      Synonyms:琥珀酸洛沙平
      分子量:445.90
      分子式:C₂₂H₂₄ClN₃O₅
      SMILES:O=C(O)CCC(O)=O.CN1CCN(C2=NC3=CC=CC=C3OC4=CC=C(Cl)C=C24)CC1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Loxapine succinate 是D2/D4多巴胺受体,5羟-色胺受体抑制剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Seeman, P., Corbett, R., and Van Tol, H.H.Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptorsNeuropsychopharmacology16(2),93-110(1997)

      Kroeze, W.K., Hufeisen, S.J., Popadak, B.A., et al.H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugsNeuropsychopharmacology28(3),519-526(2003)

      Zeller, S.L., and Citrome, L.Managing agitation associated with schizophrenia and bipolar disorder in the emergency settingWest J. Emerg. Med.17(2),165-172(2016)

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