Dolasetron
Cat. No.：YN321571
CAS No. ：115956-12-2
规格
价格(RMB)
库存
| 产品名称: | Dolasetron |
| CAS No.: | 115956-12-2 |
| Chemical Name: | 1H-indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer |
| Synonyms: | MDL-73147 |
| 分子量: | 324.37 |
| 分子式: | C₁₉H₂₀N₂O₃ |
| SMILES: | O=C(C1=CNC2=C1C=CC=C2)O[C@@H]3C[C@@](CC4C5)([H])[N@](CC4=O)[C@@]5([H])C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dolasetron (MDL-73147) 是5-HT3受体拮抗剂，有潜力用于化疗引起的恶心和呕吐。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Beoijinga, P.H., Galvan, M., Baron, B.M., et al.Characterization of the novel 5-HT3 antagonists MDL 73147EF (dolasetron mesilate) and MDL 74156 in NG108-15 neuroblastoma x glioma cellsEur. J. Pharmacol.219(1),9-13(1992)
Miller, R.C., Galvan, M., Gittos, M.W., et al.Pharmacological properties of dolasetron, a potent and selective antagonist at 5-HT3 receptorsDrug Develop. Res.28(1),87-93(1993)
