Nefazodone hydrochloride
Cat. No.：YN321652
| 产品名称: | Nefazodone hydrochloride |
| CAS No.: | 82752-99-6 |
| Chemical Name: | 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one, monohydrochloride |
| Synonyms: | BMY-13754; MJ-13754-1 |
| 分子量: | 506.47 |
| 分子式: | C₂₅H₃₃Cl₂N₅O₂ |
| SMILES: | O=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)N=C(CC)N1CCOC4=CC=CC=C4.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nefazodone hydrochloride (BMY-13754) 是一种强效和选择性的5HT2A(Ki=5.8 nM) 拮抗剂，对 5-HT 和去甲肾上腺素摄取具有中度抑制作用 (IC50分别为 290 和 300 nM)。Nefazodone hydrochloride 是一种苯哌嗪类抗抑郁药，具有微弱的 α-肾上腺素阻断活性。 |
| IC50和靶点: | [{name:"5-HT2A Receptor:5.8 nM (Ki)'}, 'α1-adrenergic receptor'] |
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