Harmine
Cat. No.:YN321729
| 产品名称: | Harmine | 
| CAS No.: | 442-51-3 | 
| Chemical Name: | 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole | 
| Synonyms: | 去氢骆驼蓬碱; Telepathine | 
| 分子量: | 212.25 | 
| 分子式: | C₁₃H₁₂N₂O | 
| SMILES: | CC1=NC=CC2=C1NC3=C2C=CC(OC)=C3 | 
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. | 
| 运输: | Room temperature in continental US; may vary elsewhere. | 
| 产品描述: | Harmine 是一种具有抗癌和抗炎活性的天然双特异性酪氨酸磷酸化调节激酶 (DYRK) 抑制剂。Harmine 对5-HT2A血清素受体具有高亲和力,Ki值为 397 nM。 | 
| IC50和靶点: | [{name:"5-HT2A Receptor:397 nM (Ki)'}, 'DYRK1A'] | 
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| Solvent & Solubility: | 
Brierley, D.I., and Davidson, C.Developments in harmine pharmacology – implications for ayahuasca use and drug-dependence treatmentProg. Neuropsychopharmacol. Biol. Psychiatry39(2),263-272(2012)
Aricioglu-Kartal, F., Kayir, H., and Uzbay, I.T.Effects of harman and harmine on naloxone-precipitated withdrawal syndrome in morphine-dependent ratsLife Sci.73(18),2363-2371(2003)