AT-121
Cat. No.：YN322109
CAS No. ：2099681-31-7
规格
价格(RMB)
库存
| 产品名称: | AT-121 |
| CAS No.: | 2099681-31-7 |
| Chemical Name: | N-[2-[1,2-dihydro-1'-[cis-4-(1-methylethyl)cyclohexyl]-3-oxospiro[isoquinoline-4(3H),4'-piperidin]-2-yl]ethyl]-sulfamide |
| Synonyms: | |
| 分子量: | 462.64968 |
| 分子式: | C24H38N4O3S |
| SMILES: | CC(C)[C@@H]1CC[C@H](N2CCC3(C(N(CCNS(N)(=O)=O)CC4=C3C=CC=C4)=O)CC2)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AT-121 是一种双功能的nociception和 mu 阿片受体 (muopioid receptor) 激动剂，Ki值分别为 3.67 和 16.49 nM。AT-121 是一种安全、无成瘾性的缓解疼痛药，具有抗伤害和止痛作用。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Ding, H., Kiguchi, N., Yasuda, D., et al.A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primatesSci. Transl. Med.10(456),eaar3483(2018)
