MLS-573151
Cat. No.：YN322125
CAS No. ：10179-57-4
规格
价格(RMB)
库存
| 产品名称: | MLS-573151 |
| CAS No.: | 10179-57-4 |
| Chemical Name: | 4-(4,5-dihydro-3,5-diphenyl-1H-pyrazol-1-yl)-benzenesulfonamide |
| Synonyms: | MLS000573151 |
| 分子量: | 377.5 |
| 分子式: | C21H19N3O2S |
| SMILES: | NS(C(C=C1)=CC=C1N2C(C3=CC=CC=C3)CC(C4=CC=CC=C4)=N2)(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MLS-573151 (MLS000573151) 是一种选择性 GTPaseCdc42的抑制剂，EC50为 2 μM。MLS-573151 对其他 GTPases 家族成员无效，例如 Rab2，Rab7，H-Ras，Rac1，Rac 2 和 RhoA 野生型。MLS-573151 通过阻止 GTP 与 Cdc42 的结合来发挥作用。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Bustelo, X.R., Sauzeau, V., and Berenjeno, I.M.GTP-binding proteins of the Rho/Rac family: Regulation, effectors and functions in vivoBioEssays29(4),356-370(2007)
Surviladze, Z., Waller, A., Wu, Y., et al.Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assayJ. Biomol. Screen.15(1),10-20(2013)
