REV 5901
Cat. No.:YN322127
| 产品名称: | REV 5901 | 
| CAS No.: | 101910-24-1 | 
| Chemical Name: | α-pentyl-3-(2-quinolinylmethoxy)-benzenemethanol | 
| Synonyms: | |
| 分子量: | 335.4 | 
| 分子式: | C22H25NO2 | 
| SMILES: | CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 | 
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. | 
| 运输: | Room temperature in continental US; may vary elsewhere. | 
| 产品描述: | REV 5901 是一种竞争性和具有口服活性的白三烯受体 (leukotriene receptor) 拮抗剂,Ki值为 0.7 μM。REV 5901 也是一种 5-脂氧合酶 (5-lipoxygenase) 抑制剂。REV 5901 可用于涉及白三烯释放的哮喘研究。 | 
| IC50和靶点: | |
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| Solvent & Solubility: | 
Van Inwegen, R.G., Khandwala, A., Gordon, R., et al.REV 5901: An orally effective peptidoleukotriene antagonist, detailed biochemical/pharmacological profileJ. Pharmacol. Exp. Ther.241,117-124(1987)
Musser, J.H., Charkraborty, U.R., Sciortino, S., et al.Substituted arylmethyl phenyl ethers. 1. A novel series of 5-lipoxygenase inhibitors and leukotriene antagonistsJ. Med. Chem.30,96-104(1987)