CGS 12066B
Cat. No.：YN322146
| 产品名称: | CGS 12066B |
| CAS No.: | 109028-10-6 |
| Chemical Name: | 4-(4-methyl-1-piperazinyl)-7-(trifluoromethyl)-pyrrolo[1,2-a]quinoxaline, (2Z)-2-butenedioate |
| Synonyms: | |
| 分子量: | 566.4833696 |
| 分子式: | C17H17F3N4 • 2C4H4O4 |
| SMILES: | FC(F)(F)C1=CC=C2C(N=C(N3CCN(C)CC3)C4=CC=CN42)=C1.OC(/C=C\C(O)=O)=O.OC(/C=C\C(O)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CGS 12066 (dimaleate) 是一种选择性的5-HT1B受体激动剂，IC50为 51 nM。 |
| IC50和靶点: | [{name:"5-HT1B Receptor:51 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Neale, R.F., Fallon, S.L., Boyar, W.C., et al.Biochemical and pharmacological characterization of CGS 12066B, a selective serotonin-1B agonistEur. J. Pharmacol.136(1),1-9(1987)
Unsworth, C.D., and Molinoff, P.B.Regulation of the 5-hydroxytryptamine1B receptor in opossum kidney cells after exposure to agonistsMol. Pharmacol.42(3),464-470(1992)
Joppa, M.A., Rowe, R.K., and Meisel, R.L.Effects of serotonin 1A or 1B receptor agonists on social aggression in male and female Syrian hamstersPharmacol. Biochem. Behav.58(2),349-353(1997)
