Meclizine dihydrochloride
Cat. No.：YN322153
| 产品名称: | Meclizine dihydrochloride |
| CAS No.: | 1104-22-9 |
| Chemical Name: | 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-piperazine, dihydrochloride |
| Synonyms: | 盐酸美克洛嗪; Meclozine dihydrochloride |
| 分子量: | 463.9 |
| 分子式: | C25H27ClN2 • 2HCl |
| SMILES: | CC1=CC=CC(CN(CC2)CCN2C(C3=CC=CC=C3)C4=CC=C(Cl)C=C4)=C1.Cl.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Meclizine (Meclozine) dihydrochloride 是一种抗组胺剂 (antihistamine)，可逆地抑制组胺与H1受体的相互作用。Meclizine dihydrochloride 是哌嗪类 H1 拮抗剂。Meclizine dihydrochloride 是一种有效的抗晕车剂。Meclizine dihydrochloride 可透过血脑屏障，可用于多聚谷氨酰胺毒性障碍（例如亨廷顿舞蹈症）方面的研究。Meclizine dihydrochloride 是小鼠组成型雄甾烷受体 |
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Tran, V.T., Chang, R.S.L., and Snyder, S.H.Histamine H1 receptors identified in mammalian brain membranes with [3H]mepyramineProc. Natl. Acad. Sci. USA75(12),6290-6294(1978)
Pasquale, C.P., e Silva, P.M., Lima, M.C., et al.Suppression by cetirizine of pleurisy triggered by antigen in actively sensitized ratsEur. J. Pharmacol.223(1),9-14(1992)
