EM574
Cat. No.:YN322154
产品名称: | EM574 |
CAS No.: | 110480-13-2 |
Chemical Name: | 8,9-didehydro-N-demethyl-9-deoxo-6-deoxy-6,9-epoxy-N-(1-methylethyl)-erythromycin |
Synonyms: | EM-574; EM574; EM 574; |
分子量: | 743.9647 |
分子式: | C39H69NO12 |
SMILES: | CC[C@H]([C@](O)(C)[C@H](O)[C@@H](C)C1=C(C)C[C@](O1)(C)[C@]([H])(O[C@@]2([H])[C@H](O)[C@@H](N(C(C)C)C)C[C@@H](C)O2)[C@@H](C)[C@@](O[C@]3([H])O[C@@H](C)[C@H](O)[C@](C)(OC)C3)([H])[C@H]4C)OC4=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | EM574 是一种在人类胃腔和兔子胃肠道里有效的motilin receptor激动剂。EM574 是一种 erythromycin 衍生物。 |
IC50和靶点: | |
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Sato, F., Sekiguchi, M., Marui, S., et al.EM574, an erythromycin derivative, is a motilin receptor agonist in the rabbitEur. J. Pharmacol.322(1),63-71(1997)
Satoh, M., Sakai, T., Fujikura, K., et al.EM574, an erythromycin derivative, is a potent motilin receptor agonist in human gastric antrumJ. Pharmacol. Exp. Ther.271(1),574-579(1994)
Sato, F., Marui, S., Inatomi, N., et al.EM574, an erythromycin derivative, improves delayed gastric emptying of semi-solid meals in conscious dogsEur. J. Pharmacol.395(2),165-172(2000)